Lactoferrin: properties and benefits of this bioactive protein

In addition to its high nutritional value, milk is made up of bioactive proteins that modulate key bodily functions by acting on the immune, cardiovascular, digestive and nervous systems. Armor Protéines, thanks to its expertise acquired over many years, offers milk-derived bioactives such as Lactoferrin (Vitalarmor® Lactoferrin and Vitalarmor® Lactoferrin Organic) and Lactoperoxidase (Vitalarmor® LP).

Lactoferrin: a protein naturally present in the body

Little known among the general public, lactoferrin is one of the proteins found in the milk of mammals. More precisely, it is the second most abundant serum protein in human milk (≈1 to 2 g/L). This glycoprotein belongs to the transferrin family and is naturally present in our bodies. In particular, it is found in external secretions such as saliva and tears. Lactoferrin is best known for its ability to transport iron. In fact, lactoferrin and iron are two natural allies that contribute to the proper functioning of the body.

It was first discovered in 1939, during a study of bovine milk production, before being isolated in 1960. Widely used in the composition of various products in Asia, lactoferrin is gradually carving out a place for itself in France and elsewhere around the world.

What are the benefits of lactoferrin? 

Lactoferrin has numerous benefits for both adults and infants.

Boosts the immune system

Lactoferrin has an immunomodulatory effect, i.e. it contributes to the proper functioning of the immune system. The capacity of bovine lactoferrin to enhance the body's natural defenses is why it is present in a product such as infant milk. Very well tolerated by most newborn babies, this protein positively modulates their gut bacteria. It also promotes the development of their cognitive system and brain*. The addition of lactoferrin to infant milk forms an optimal combination that provides a good supply of nutrients for newborn babies.

Helps regulate iron levels

Thanks to its structure, lactoferrin can easily bind and transport iron, an essential nutrient for DNA replication, cell proliferation and energy production. While iron makes an important contribution to the functioning of the body, a surplus can be toxic and lead to serious health problems.

The role of lactoferrin is to sequester iron, thereby helping to regulate the homeostasis of this chemical element and the development of certain bacteria.

Antioxidant benefits

Lactoferrin also prevents cell oxidation. This activity reduces oxidative stress, which has a direct impact on chronic degenerative processes such as aging.

Antimicrobial and antiviral properties

Lactoferrin is an effective shield against the development of many bacteria, such as Streptococcus, Salmonella, Shigella, Staphylococcus and Enterobacteriaceae, as well as fungi, parasites and viruses.

In addition, this protein interacts with monocytes and macrophages to reduce inflammation.

How can lactoferrin be used?

Lactoferrin is a protein with high nutritional value, whose use can therefore be extended to a number of markets, including:

• Infant nutrition: lactoferrin offers properties similar to those of breast milk lactoferrin.
• Food supplements: for action on the immune system, for example, it can be administered in capsule form. However, customers are advised to seek medical advice before taking any other dietary supplements (vitamins, etc.).
• Lactoferrin also has a place in the diet, particularly in dairy products.
• Cosmetics: its antibacterial and antioxidant actions make it a valuable ingredient in the composition of skincare products.
• Oral hygiene: its ability to regulate iron slows the development of bacteria that cause cavities and bad breath.

Interested in adding lactoferrin to your products? Armor Protéines has developed Vitalarmor® Lactoferrin and Vitalarmor® Lactoferrin Organic, highly purified lactoferrin.

*Li & Guo, 2012 or Ochoa & Sizonenko 2017